Orthopedic Biomaterials by Bingyun Li & Thomas Webster

Author:Bingyun Li & Thomas Webster
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham

For in vivo experiments, porous Ti6Al4V and Mg coated porous samples were implanted into the lateral femoral epicondyle of New Zealand white rabbits. Cylindrical defects (Ф6 mm × 8 mm) were drilled, and the porous scaffold were randomly filled into the defects. The newly formed bone in group B (Fig. 22B1, D1) was much more than that in group A (Fig. 22A1, C1), and bone was observed to grow deeply into the scaffold with Mg coating. While newly formed bone was confined near the edge of the scaffold and few grew deep into the bare scaffold. The above results revealed that the Mg coating substantially improved the osteogenesis and osteointegration properties of porous Ti6Al4V scaffolds.

Fig. 22Micro-CT images of the bare porous Ti6Al4V (a1 and c1) and Mg coated porous Ti6Al4V (b1 and d1) at 4 and 8 weeks after implantation. The yellow colour was newly formed bone on these scaffolds [160]

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